产品详情
简单介绍:
Anti-ECSIT Antibody
详情介绍:
Overview
Name: | Anti-ECSIT Antibody See all ECSIT primary antibodies
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Description: | Rabbit polyclonal antibody to ECSIT |
Applications: | E, WB, IHC |
Reactivity: | Human, Mouse |
Immunogen: | Raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT. |
Host: | Rabbit |
Clonality: | Polyclonal |
Conjugate: | Unconjugated |
Purification: | Ion exchange chromatography purified |
Formulation: | Supplied in PBS containing 0.02% sodium azide. |
Storage: | Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Target
Function: | Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development. |
Tissue Specificity: | Detected in heart, brain, lung, liver, skeletal muscle, kidney and testis. Detected in embryonic mesoderm and epiblast, and in extraembryonic ectoderm. |
Sequence Similarities: | Belongs to the ECSIT family. |
Cellular Location: | Cytoplasm. Nucleus. Mitochondrion. |
Database Links: |
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Synonyms: | |
Information: | Target information shown above is from the UniProt Consortium. |
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