产品详情
简单介绍：
Anti-EEF1A1 Antibody
详情介绍：
Overview
| Name: | Anti-EEF1A1 Antibody See all EEF1A1 primary antibodies
|
| Description: | Rabbit polyclonal antibody to EEF1A1. |
| Applications: | WB, IHC, IF |
| Dilutions: | WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:20 - 1:100. |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant protein of human EEF1A1. |
| Protein Length: | 462 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Purification: | Affinity purification. |
| Product Form: | Liquid |
| Formulation: | Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
| Function: | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. |
| Tissue Specificity: | Brain, placenta, lung, liver, kidney, pancreas but barely detectable in heart and skeletal muscle. |
| Sequence Similarities: | Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. |
| Post-Translational Modification: | ISGylated. |
| Cellular Location: | Cytoplasm. Nucleus. Nucleus > Nucleolus. Colocalizes with DLC1 at actin-rich regions in the cell periphery. Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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