产品详情
简单介绍：
Anti-EF-1 α1 / 2 (Acetyl-Lys41) Antibody
详情介绍：
Overview
| Name: | Anti-EF-1 α1 / 2 (Acetyl-Lys41) Antibody See all EF-1 α1 primary antibodies
|
| Description: | Rabbit polyclonal antibody to EF-1 α1 / 2 (Acetyl-Lys41) |
| Specificity: | Acetyl-EF-1 α1 / 2 (K41) Polyclonal Antibody detects endogenous levels of EF-1 α1 / 2 protein only when acetylated at K41. |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from the human EF-1 α1 / 2 around the acetylation site of K41. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1mg / ml |
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage: | Store at -20˚C / 1 year |
Target
| Function: | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. |
| Tissue Specificity: | Brain, placenta, lung, liver, kidney, pancreas but barely detectable in heart and skeletal muscle. |
| Sequence Similarities: | Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. |
| Post-Translational Modification: | ISGylated. |
| Cellular Location: | Cytoplasm. Nucleus. Nucleus > Nucleolus. Colocalizes with DLC1 at actin-rich regions in the cell periphery. Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens. |
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