产品详情
简单介绍:
Anti-EIF2C3 Antibody
详情介绍:
Overview
Name: | Anti-EIF2C3 Antibody See all EIF2C3 primary antibodies
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Description: | Rabbit polyclonal antibody to EIF2C3 |
Applications: | ELISA, WB, IHC |
Reactivity: | Human, Mouse, Rat |
Immunogen: | Rabbit polyclonal EIF2C3(1) antibody was raised against a peptide from the intermediate residues of human EIF2C3 protein. |
Host: | Rabbit |
Clonality: | Polyclonal |
Conjugate: | Unconjugated |
Purification: | Affinity purified |
Concentration: | 1.0mg / ml |
Formulation: | PBS, pH 7.4 with 0.02% sodium azide. |
Storage: | This product is stable for several weeks at 4?C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20?C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
Target
Function: | Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. |
Sequence Similarities: | Belongs to the argonaute family. Ago subfamily. |
Cellular Location: | Cytoplasm > P-body. |
Database Links: |
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Synonyms: | |
Information: | Target information shown above is from the UniProt Consortium. |
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