产品详情
简单介绍：
Anti-EIF5B Antibody
详情介绍：
Overview
| Name: | Anti-EIF5B Antibody See all EIF5B primary antibodies
|
| Description: | Rabbit polyclonal antibody to EIF5B |
| Specificity: | The antibody detects endogenous level of total EIF5B antibody. |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant protein of human EIF5B. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antibodies were purified by affinity purification using immunogen. |
| Concentration: | 1.0mg / ml |
| Formulation: | Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage: | Store at -20˚C |
Target
| Function: | Plays a role in translation initiation. Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon. GTP binding and hydrolysis induces conformational changes in the enzyme that renders it active for productive interactions with the ribosome. The release of the enzyme after formation of the initiation complex is a prerequisite to form elongation-competent ribosomes. |
| Sequence Similarities: | Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. |
| Cellular Location: | Cytoplasm. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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