产品详情
简单介绍:
Anti-Elongin A1 (R129) Antibody
详情介绍:
Overview
Name: | Anti-Elongin A1 (R129) Antibody See all Elongin A1 primary antibodies
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Description: | Rabbit polyclonal antibody to Elongin A1 (R129) |
Specificity: | Elongin A1 (R129) pAb detects endogenous levels of Elongin A1 protein. |
Applications: | WB, IHC |
Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide, corresponding to amino acids 98-142 of Human Elongin A1. |
Host: | Rabbit |
Clonality: | Polyclonal |
Conjugate: | Unconjugated |
Molecular Weight: | ~78 kDa |
Purity: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Product Form: | 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. |
Target
Function: | SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). |
Cellular Location: | Nucleus. |
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