产品详情
简单介绍：
Anti-ELOVL6 Antibody
详情介绍：
Overview
| Name: | Anti-ELOVL6 Antibody See all ELOVL6 primary antibodies
|
| Description: | Rabbit polyclonal antibody to ELOVL6 |
| Specificity: | The antibody detects endogenous levels of total ELOVL6 protein. |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide corresponding to a region derived from internal residues of human ELOVL fatty acid elongase 6 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antigen affinity purification. |
| Concentration: | 2.4mg / ml |
| Formulation: | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Storage: | Store at -20?C |
Target
| Function: | Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
| Tissue Specificity: | Ubiquitous. |
| Sequence Similarities: | Belongs to the ELO family. ELOVL6 subfamily. |
| Post-Translational Modification: | N-Glycosylated. |
| Cellular Location: | Endoplasmic reticulum membrane. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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