产品详情
简单介绍：
Anti-EMMPRIN Antibody
详情介绍：
Overview
| Name: | Anti-EMMPRIN Antibody See all EMMPRIN primary antibodies
|
| Description: | Rabbit polyclonal antibody to EMMPRIN |
| Specificity: | EMMPRIN Polyclonal Antibody detects endogenous levels of EMMPRIN protein. |
| Applications: | WB, IHC, ELISA |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human EMMPRIN. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1mg / ml |
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage: | Store at -20?C / 1 year |
Target
| Function: | Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. |
| Tissue Specificity: | Present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas. |
| Post-Translational Modification: | N-glycosylated. |
| Cellular Location: | Cell membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In spermatozoa, localized on the principal piece of caput and in the middle piece during transit in the corpus and cauda epididymides (By similarity). |
| Database Links: |
|
| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
相关文章
