产品详情
简单介绍：
Anti-Enolase 3 Antibody
详情介绍：
Overview
| Name: | Anti-Enolase 3 Antibody See all Enolase3 primary antibodies
|
| Description: | Rabbit polyclonal antibody to Enolase 3 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Immunogen: | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 196 and 413 of human ENO3 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Purified by antigen-affinity chromatography. |
| Formulation: | Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. |
| Storage: | Store at -20?C for long term preservation (recommended). Store at 4?C for short term use. |
Target
| Function: | Appears to have a function in striated muscle development and regeneration. |
| Tissue Specificity: | The alpha/alpha homodimer is expressed in embryo and in most ***** tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. |
| Involvement in Disease: | Glycogen storage disease 13: A metabolic disorder that results in exercise-induced myalgias, generalized muscle weakness and fatigability. It is characterized by increased serum creatine kinase and decreased enolase 3 activity. Dramatically reduced protein levels with focal sarcoplasmic accumulation of glycogen-beta particles are detected on ultrastructural analysis. |
| Sequence Similarities: | Belongs to the enolase family. |
| Cellular Location: | Cytoplasm. Localized to the Z line. Some colocalization with CKM at M-band (By similarity). |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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