产品详情
简单介绍：
Anti-EPS15L1 Antibody
详情介绍：
Overview
| Name: | Anti-EPS15L1 Antibody See all EPS15L1 primary antibodies
|
| Description: | Rabbit polyclonal antibody to EPS15L1 |
| Specificity: | The antibody detects endogenous levels of total EPS15L1 protein. |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Immunogen: | Fusion protein corresponding to residues near the C terminal of human epidermal growth factor receptor pathway substrate 15-like 1 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antigen affinity purification. |
| Concentration: | 1.4mg / ml |
| Formulation: | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Storage: | Store at -20?C |
Target
| Function: | Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. |
| Post-Translational Modification: | Phosphorylated on tyrosine residues by EGFR. |
| Cellular Location: | Cell membrane. Nucleus. Membrane > Coated pit. Localized to plasma membrane coated pits. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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