产品详情
简单介绍：
Anti-EPX Antibody
详情介绍：
Overview
| Name: | Anti-EPX Antibody See all EPX primary antibodies
|
| Description: | Rabbit polyclonal antibody to EPX |
| Specificity: | The antibody detects endogenous levels of total EPX protein. |
| Applications: | IHC |
| Reactivity: | Human |
| Immunogen: | Synthetic peptide of human EPX |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antigen affinity purification |
| Concentration: | 0.2mg / ml |
| Formulation: | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Storage: | Store at -20?C |
Target
| Function: | Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis. |
| Involvement in Disease: | Eosinophil peroxidase deficiency: A rare abnormality without clinical symptoms characterized by decreased or absent peroxidase activity and decreased volume of the granule matrix in eosinophils. |
| Sequence Similarities: | Belongs to the peroxidase family. XPO subfamily. |
| Cellular Location: | Cytoplasmic granule. Cytoplasmic granules of eosinophils. |
| Database Links: |
|
| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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