产品详情
简单介绍:
Anti-ETEA Antibody
详情介绍:
Overview
Name: | Anti-ETEA Antibody See all ETEA primary antibodies
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Description: | Rabbit polyclonal antibody to ETEA |
Applications: | WB, IHC |
Reactivity: | Human |
Immunogen: | Synthetic peptide contain a sequence corresponding to a region within amino acids 383 and 395 (Q96CS3) of ETEA |
Host: | Rabbit |
Clonality: | Polyclonal |
Conjugate: | Unconjugated |
Purification: | Purified by antigen-affinity chromatography. |
Formulation: | Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. |
Storage: | Store at -20?C for long term preservation (recommended). Store at 4?C for short term use. |
Target
Function: | Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:18711132, PubMed:24215460). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis (PubMed:23297223). |
Tissue Specificity: | Broadly expressed, with highest levels in brain. |
Cellular Location: | Cytoplasm. Lipid droplet. Endoplasmic reticulum. |
Database Links: |
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Synonyms: | |
Information: | Target information shown above is from the UniProt Consortium. |
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