产品详情
简单介绍：
Anti-ETV1 Antibody
详情介绍：
Overview
| Name: | Anti-ETV1 Antibody See all ETV1 primary antibodies
|
| Description: | Rabbit polyclonal antibody to ETV1. |
| Applications: | WB, IHC, IF |
| Dilutions: | WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100. |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant protein of human ETV1. |
| Protein Length: | 477 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Purification: | Affinity purification. |
| Product Form: | Liquid |
| Formulation: | Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
| Function: | Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'. |
| Tissue Specificity: | Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes. |
| Involvement in Disease: | Ewing sarcoma: A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors. |
| Sequence Similarities: | Belongs to the ETS family. |
| Post-Translational Modification: | Sumoylated. |
| Cellular Location: | Nucleus. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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