产品详情
简单介绍:
Anti-EXOC7 Antibody
详情介绍:
Overview
Name: | Anti-EXOC7 Antibody See all EXOC7 primary antibodies
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Description: | Rabbit polyclonal antibody to EXOC7 |
Applications: | WB, IF |
Reactivity: | Human |
Immunogen: | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 74 and 345 of EXOC7 |
Host: | Rabbit |
Clonality: | Polyclonal |
Conjugate: | Unconjugated |
Purification: | Purified by antigen-affinity chromatography. |
Formulation: | Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. |
Storage: | Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use. |
Target
Function: | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion (By similarity). |
Sequence Similarities: | Belongs to the EXO70 family. |
Cellular Location: | Cytoplasm > Cytosol. Cell membrane. Midbody > Midbody ring. Translocates, as a preformed complex with EXOC3/SEC6 and EXOC4/SEC8, to the plasma membrane in response to insulin through the activation of ARHQ (By similarity). Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). |
Database Links: |
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Synonyms: | |
Information: | Target information shown above is from the UniProt Consortium. |
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