产品详情
简单介绍：
Anti-F11R Antibody
详情介绍：
Overview
| Name: | Anti-F11R Antibody See all F11R primary antibodies
|
| Description: | Rabbit polyclonal antibody to F11R |
| Specificity: | The antibody detects endogenous level of total F11R protein. |
| Applications: | WB, IHC, IF |
| Reactivity: | Human |
| Immunogen: | Recombinant protein of human F11R. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antibodies were purified by affinity purification using immunogen. |
| Concentration: | 1.0mg / ml |
| Formulation: | Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage: | Store at -20?C |
Target
| Function: | Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840). |
| Tissue Specificity: | Expressed in endothelium, epithelium and leukocytes (at protein level). |
| Sequence Similarities: | Belongs to the immunoglobulin superfamily. |
| Post-Translational Modification: | N-glycosylated. |
| Cellular Location: | Cell junction > Tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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