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  • 产品名称:Anti-F1A alpha Antibody

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简单介绍:
Anti-F1A alpha Antibody
详情介绍:
Name: Anti-F1A alpha Antibody
See all F1A alpha primary antibodies
Description: Rabbit polyclonal antibody to F1A alpha
Applications: E, WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Raised against a peptide corresponding to amino acids 609 to 622 of human F1A alpha. This sequence is identical to the corresponding sequence of mouse FEM1b.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Affinity chromatography purified via peptide column
Formulation: Supplied in PBS containing 0.02% sodium azide.
Storage: Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Function: Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet (By similarity). Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1 (By similarity).
Tissue Specificity: Present in ***** testis (at protein level).
Sequence Similarities: Belongs to the fem-1 family.
Cellular Location: Cytoplasm. Nucleus.

Associated with chromatin.
Database Links:
  • Entrez Gene: 10116?Human
  • Entrez Gene: 14155?Mouse
  • Entrez Gene: 315745?Rat
  • Omim: 613539?Human
  • SwissProt: Q9UK73?Human
  • SwissProt: Q9Z2G0?Mouse
  • SwissProt: P0C6P7?Rat
  • Unigene: 362733?Human
  • Unigene: 24069?Mouse
  • Unigene: 219320?Rat
  • Synonyms:
  • F1A alpha Antibody
  • F1A-alpha Antibody
  • F1AA Antibody
  • FEM 1B Antibody
  • Fem-1-like death receptor-binding protein alpha Antibody
  • Fem-1-like in apoptotic pathway protein alpha Antibody
  • Fem1 homolog b Antibody
  • FEM1 like death receptor binding protein Antibody
  • FEM1-beta Antibody
  • FEM1b Antibody
  • FEM1B_HUMAN Antibody
  • Protein fem-1 homolog B Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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