产品详情
简单介绍：
Anti-FABP6 Antibody
详情介绍：
Overview
| Name: | Anti-FABP6 Antibody See all FABP6 primary antibodies
|
| Description: | Rabbit polyclonal antibody to FABP6 |
| Specificity: | The antibody detects endogenous levels of total FABP6 protein. |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Immunogen: | Full length fusion protein |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antigen affinity purification. |
| Concentration: | 1.1mg / ml |
| Formulation: | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Storage: | Store at -20?C |
Target
| Function: | Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity). |
| Tissue Specificity: | Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). |
| Sequence Similarities: | Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
| Cellular Location: | Cytoplasm. Membrane. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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