产品详情
简单介绍：
Anti-FAH Antibody
详情介绍：
Overview
| Name: | Anti-FAH Antibody See all FAH primary antibodies
|
| Description: | Rabbit polyclonal antibody to FAH |
| Specificity: | FAH polyclonal antibody detects endogenous levels of FAH protein. |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant full length Human FAH. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Molecular Weight: | ~ 46 kDa |
| Purity: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
| Product Form: | 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol. |
Target
| Tissue Specificity: | Mainly expressed in liver and kidney. Lower levels are also detected in many other tissues. |
| Involvement in Disease: | Tyrosinemia 1: An inborn error of metabolism characterized by elevations of tyrosine in the blood and urine, and hepatorenal manifestations. Typical features include hepatic necrosis, renal tubular injury, episodic weakness, self-mutilation, and seizures. Renal tubular dysfunction is associated with phosphate loss and hypophosphataemic rickets. Progressive liver disease can lead to the development of hepatocellular carcinoma. Dietary treatment with restriction of tyrosine and phenylalanine alleviates the rickets, but liver transplantation has so far been the only definite treatment. |
| Sequence Similarities: | Belongs to the FAH family. |
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