产品详情
简单介绍：
Anti-FAM120A Antibody
详情介绍：
Overview
| Name: | Anti-FAM120A Antibody See all FAM120A primary antibodies
|
| Description: | Rabbit polyclonal antibody to FAM120A |
| Specificity: | This antibody will not cross-reacti with FAM120B / PGCC1. |
| Applications: | E, WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Raised against an 18 amino acid peptide from near the center of human FAM120A. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Affinity chromatography purified via peptide column |
| Formulation: | Supplied in PBS containing 0.02% sodium azide. |
| Storage: | Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Target
| Function: | Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II (By similarity). May participate in mRNA transport in the cytoplasm. |
| Tissue Specificity: | Present in Purkinje cells in the cerebellum, and in cortical neurons (at protein level). |
| Sequence Similarities: | Belongs to the constitutive coactivator of PPAR-gamma family. |
| Post-Translational Modification: | Arg-980 is dimethylated, probably to asymmetric dimethylarginine. |
| Cellular Location: | Cytoplasm. Cell membrane. Translocates to plasma membrane upon ultraviolet exposure. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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