产品详情
简单介绍：
Anti-FANCF Antibody
详情介绍：
Overview
| Name: | Anti-FANCF Antibody See all FANCF primary antibodies
|
| Description: | Goat polyclonal antibody to FANCF. |
| Applications: | ELISA, WB |
| Reactivity: | Human |
| Immunogen: | Synthetic peptide corresponding to Human FANCF (internal region). |
| Sequence: | C-RPQEELEPGIHK |
| Host: | Goat |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 100 µg at 0.5 mg/ml. |
| Product Form: | Liquid |
| Formulation: | Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
| Function: | DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability (By similarity). |
| Involvement in Disease: | Fanconi anemia complementation group F: A disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair. |
| Cellular Location: | Nucleus. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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