产品详情
简单介绍：
Anti-FASTK Antibody
详情介绍：
Overview
| Name: | Anti-FASTK Antibody See all FASTK primary antibodies
|
| Description: | Rabbit polyclonal antibody to FASTK |
| Specificity: | The antibody detects endogenous levels of total FASTK protein. |
| Applications: | IHC |
| Reactivity: | Human |
| Immunogen: | Fusion protein corresponding to residues near the C terminal of human fas-activated serine / threonine kinase |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antigen affinity purification. |
| Concentration: | 1.3mg / ml |
| Formulation: | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Storage: | Store at -20?C |
Target
| Function: | Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor. |
| Tissue Specificity: | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Sequence Similarities: | Belongs to the FAST protein kinase family. |
| Post-Translational Modification: | Autophosphorylated on serine/threonine residues. Activated by dephosphorylation. |
| Cellular Location: | Mitochondrion matrix. Colocalizes with mitochondrial RNA granules. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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