产品详情
简单介绍：
Anti-FBLN1 Antibody
详情介绍：
Overview
| Name: | Anti-FBLN1 Antibody See all FBLN1 primary antibodies
|
| Description: | Rabbit polyclonal antibody to FBLN1 |
| Specificity: | The antibody detects endogenous levels of total FBLN1 protein. |
| Applications: | IHC |
| Reactivity: | Human |
| Immunogen: | Synthetic peptide corresponding to a region derived from internal residues of human fibulin 1 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antigen affinity purification. |
| Concentration: | 1.9mg / ml |
| Formulation: | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Storage: | Store at -20?C |
Target
| Function: | Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP. |
| Tissue Specificity: | Isoform A and isoform B are only expressed in placenta. Isoform C and isoform D are expressed in a variety of tissues and cultured cells. |
| Sequence Similarities: | Belongs to the fibulin family. |
| Cellular Location: | Secreted > Extracellular space > Extracellular matrix. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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