产品详情
简单介绍：
Anti-FBP2 Antibody
详情介绍：
Overview
| Name: | Anti-FBP2 Antibody See all FBP2 primary antibodies
|
| Description: | Rabbit polyclonal antibody to FBP2 |
| Specificity: | The antibody detects endogenous levels of total FBP2 protein. |
| Applications: | IHC |
| Reactivity: | Human |
| Immunogen: | Full length fusion protein |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Antigen affinity purification. |
| Concentration: | 2mg / ml |
| Formulation: | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Storage: | Store at -20?C |
Target
| Function: | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. |
| Tissue Specificity: | Expressed in skeletal muscle (at protein level). |
| Sequence Similarities: | Belongs to the FBPase class 1 family. |
| Cellular Location: | Cell junction. Cytoplasm. Nucleus. Cytoplasm > Myofibril > Sarcomere > Z line. In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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