产品详情
简单介绍：
Anti-FBXL12 Antibody
详情介绍：
Overview
| Name: | Anti-FBXL12 Antibody See all FBXL12 primary antibodies
|
| Description: | Rabbit polyclonal antibody to FBXL12 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide contain a sequence corresponding to a region within amino acids 265 and 326 of FBXL12 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Purification: | Purified by antigen-affinity chromatography. |
| Formulation: | Supplied in 1XPBS, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. |
| Storage: | Store at -20?C for long term preservation (recommended). Store at 4?C for short term use. |
Target
| Function: | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the polyubiquitination and proteasomal degradation of CAMK1 leading to disruption of cyclin D1/CDK4 complex assembly which results in G1 cell cycle arrest in lung epithelia (By similarity). |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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