产品详情
简单介绍:
Human Lactoferrin
详情介绍:
Native Protein
Human Lactoferrin
N/A
10mg/1mg
one week
Purified from Human milk
Full length protein
ELISA, WB, SDS-PAGE
>95% (SDS-PAGE)
Lactoferrin is a glycoprotein present in most human mucosal secretions, including human milk. Lactoferrin is bacteriostatic in low iron media and, in some settings, bactericidal. Lactoferrin impairs ability of Shigella flexneri serotype 5 strain M90T to invade HeLa cells. To determine the mechanism by which lactoferrin decreases invasiveness of Shigella organisms, its effect on the major virulence proteins responsible for bacterial uptake by host cells was evaluated. Lactoferrin induced degradation of invasion plasmid antigens IpaB and, to a lesser extent, IpaC, the key proteins responsible for bacteria-directed phagocytosis by mammalian cells.
PBS, pH 7.4
Liquid
Aliquot and store at -20℃ or -80℃. Avoid repeated freeze/thaw cycles.
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human Lactoferrin
Not test
Cardiovascular
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