产品类型:

Growth Factor

产品名称:

Recombinant Human Pro-epidermal growth factor protein(EGF) (Active)

uniprot号:

规格:

100μg 500μg ￥100

图像:

基因名称:

EGF

别名:

EGF,]

种属:

Homo sapiens (Human)

蛋白描述:

Partial

PubMed ID:

3491360; 14702039; 15815621; 15489334; 300079; 2789514; 22171320; 1522591; 10964941; 17671655; 21439629; 11438527; 12297050; 12620237; 21029725; 20837704

分子量:

6.2 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>98% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 m filtered 20 mM PB, pH 7.2 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 0.1 ng/ml, corresponding to a specific activity of >1.0x10⁷ IU/mg.

Uniprot登录名:

EGF_HUMAN

参考文献:

EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941). {ECO:0000269|PubMed:10964941, ECO:0000269|PubMed:17671655}.

氨基酸序列:

NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR

表达区域:

971-1023aa

研究领域:

Cancer