产品类型:

Recombinant Protein

产品名称:

Recombinant Human C-C chemokine receptor type 2(CCR2)

uniprot号:

规格:

100ug 50ug 10ug

图像:

基因名称:

CCR2

别名:

Monocyte chemoattractant protein 1 receptor Short name:MCP-1-R CMKBR2

种属:

Homo sapiens (Human)

蛋白描述:

Full Length

分子量:

45.4 kDa

标签信息:

N-terminal 10xHis-tagged

来源:

in vitro E.coli expression system

纯度:

Greater than 85% as determined by SDS-PAGE.

缓冲液:

Tris-based buffer，50% glycerol

生物活性:

Measured by its binding ability in a functional ELISA. Immobilized CCR2 at 1 μg/ml can bind human CCL2, the EC50 of human CCL2 protein is 41.51-83.15 μg/ml.

氨基酸序列:

MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGNMLVVLILINC
KKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYL
AIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKCQKEDSVYVCGPYFPRGWNNFHTIMRNILG
LVLPLLIMVICYSGILKTLLRCRNEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCEST
SQLDQATQVTETLGMTHCCINPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGL
LDGRGKGKSIGRAPEASLQDKEGA

简介:

Receptor for the CCL2, CCL7 and CCL13 chemokines. Receptor for the beta-defensin DEFB106A/DEFB106B. Transduces a signal by increasing intracellular calcium ion levels. Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable).

蛋白储存:

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

表达区域:

1-374aa

使用注意:

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

研究领域:

Cancer