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Recombinant Human herpesvirus 8 type P protein(VMI2) (Active)
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Recombinant Human herpesvirus 8 type P protein(VMI2) (Active)
¥620
ORF K4
Viral macrophage inflammatory protein II
Short name:vMIP-II
vMIP-1B
Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Partial
8939871
8.0 kDa
Tag-Free
E.Coli
>97% as determined by SDS-PAGE and HPLC.
0.2 μm filtered PBS, pH 7.4 ,lyophilized
Less than 1.0 EU/μg as determined by LAL method.
Fully biologically active when compared to standard. The specific activity is determined by the inhibitory effect on monocyte migration response to human MIP-1 alpha using a concentration range of 1.0ug-10.0ug/ml of viral MIP-2 will inhibit 25ng/ml of human MIP-1 alpha.
VMI2_HHV8P
Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
LGASWHRPDK CCLGYQKRPL PQVLLSSWYP TSQLCSKPGV IFLTKRGRQV CADKSKDWVK KLMQQLPVTA
24-93aa
Immunology
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