产品类型:

Growth Factor

产品名称:

Recombinant Human Placenta growth factor protein(PGF) (Active)

uniprot号:

规格:

5μg 25μg ￥620

基因名称:

PGF

别名:

PlGF

种属:

Homo sapiens (Human)

蛋白描述:

Full Length of Isoform PlGF-2

PubMed ID:

1924389; 8148155; 7681160; 9207183; 12508121; 15489334; 7929268; 21215706; 11069911

分子量:

34.6 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>97% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4, with 0.02 % Tween-20 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The biologically active as determined by its ability to chemoattract human monocytes using a concentration range of 5.0-50 ng/ml.

Uniprot登录名:

PLGF_HUMAN

参考文献:

Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. {ECO:0000269|PubMed:21215706}.

氨基酸序列:

LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCHLCGDAVP RR

表达区域:

19-170aa

研究领域:

Cancer