产品类型:

Colony Stimulating Factor

产品名称:

Recombinant Human Thymic stromal lymphopoietin protein(TSLP) (Active)

uniprot号:

规格:

2μg 10μg 100μg 250μg ￥620

图像:

基因名称:

TSLP

种属:

Homo sapiens (Human)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

11418668; 11480573; 15372022; 15489334; 17242164; 24850429

分子量:

15.1 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>98% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered 20 mM PB, pH 7.4, 150 mM NaCl ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human IL-7Rα and human TSLP R co-transfected murine BaF3 pro-B cells is less than 0.3 ng/ml, corresponding to a specific activity of >3.3x10⁶ IU/mg.

Uniprot登录名:

TSLP_HUMAN

参考文献:

Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. {ECO:0000269|PubMed:11418668, ECO:0000269|PubMed:11480573, ECO:0000269|PubMed:17242164}.; Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin. {ECO:0000269|PubMed:24850429}.

氨基酸序列:

M+YDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKEM FAMKTKAALA IWCPGYSETQ INATQAMKKR RKRKVTTNKC LEQVSQLQGL WRRFNRPLLK QQ

表达区域:

29-159aa

研究领域:

Immunology