产品类型:

Growth Factor

产品名称:

Recombinant Human Insulin-like growth factor-binding protein 5 protein(IGFBP5) (Active)

uniprot号:

规格:

5μg 25μg 100μg 250μg ￥620

图像:

基因名称:

IGFBP5

别名:

IBP-5, IGFBP-5

种属:

Homo sapiens (Human)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

1850258; 1709938; 7511611; 15489334; 1850257; 9883900; 22117064; 26091039; 9822601

分子量:

28.6 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>96% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.0 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 cells is less than 0.4 μg/ml, corresponding to a specific activity of >2500 IU/mg in the presence of 15 ng/ml of rHuIGF-II.

Uniprot登录名:

IBP5_HUMAN

参考文献:

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

氨基酸序列:

LGSFVHCEPC DEKALSMCPP SPLGCELVKE PGCGCCMTCA LAEGQSCGVY TERCAQGLRC LPRQDEEKPL HALLHGRGVC LNEKSYREQV KIERDSREHE EPTTSEMAEE TYSPKIFRPK HTRISELKAE AVKKDRRKKL TQSKFVGGAE NTAHPRIISA PEMRQESEQG PCRRHMEASL QELKASPRMV PRAVYLPNCD RKGFYKRKQC KPSRGRKRGI CWCVDKYGMK LPGMEYVDGD FQCHTFDSSN VE

表达区域:

21-272aa

研究领域:

Cancer