产品类型:

Tumor Necrosis Factor

产品名称:

Recombinant Human Tumor necrosis factor receptor superfamily member 17 protein(TNFRSF17) (Active)

uniprot号:

规格:

5μg 20μg 100μg 250μg ￥620

图像:

基因名称:

TNFRSF17

别名:

B-cell maturation protein

种属:

Homo sapiens (Human)

蛋白描述:

Partial

PubMed ID:

1396583; 8165126; 11528522; 17825416; 10493829; 15616553; 10903733; 10801128; 10973284; 10908663; 12721620; 15542592

分子量:

5.4 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>98% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered 30 % acetonitrile, 0.1 % TFA ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40 ng/ml, corresponding to a specific activity of >2.5x10⁴ IU/mg in the presence of 100 ng/ml human APRIL.

Uniprot登录名:

TNR17_HUMAN

参考文献:

Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. {ECO:0000269|PubMed:10801128, ECO:0000269|PubMed:10903733, ECO:0000269|PubMed:10973284}.

氨基酸序列:

AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA

表达区域:

5-54aa

研究领域:

Cancer