产品类型:

Tumor Necrosis Factor

产品名称:

Recombinant Human Tumor necrosis factor receptor superfamily member 11A protein(TNFRSF11A) (Active)

uniprot号:

规格:

20μg 100μg 250μg ￥620

图像:

基因名称:

TNFRSF11A

别名:

Osteoclast differentiation factor receptor, Receptor activator of NF-KB, CD antigen CD265

种属:

Homo sapiens (Human)

蛋白描述:

Partial

PubMed ID:

9367155; 23664977; 9878548; 9774460; 15750601; 18669648; 10615125; 18606301

分子量:

19.1 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>98% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered 20 mM Tris-HCl, pH 8.0, 150mM NaCl ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit sRANK Ligand induced nuclear factor kappa B(NFkappaB) in RAW 264.7 cells is less than 50 ng/ml, corresponding to a specific activity of >2.0x10⁴ IU/mg in the presence of 15 ng/ml of recombinant sRANK Ligand.

Uniprot登录名:

TNR11_HUMAN

参考文献:

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. {ECO:0000269|PubMed:9878548}.

氨基酸序列:

QIAPPCTSEK HYEHLGRCCN KCEPGKYMSS KCTTTSDSVC LPCGPDEYLD SWNEEDKCLL HKVCDTGKAL VAVVAGNSTT PRRCACTAGY HWSQDCECCR RNTECAPGLG AQHPLQLNKD TVCKPCLAGY FSDAFSSTDK CRPWTNCTFL GKRVEHHGTE KSDAVCSSSL PARK

表达区域:

29-202aa

研究领域:

Cancer