产品类型:

Other

产品名称:

Recombinant Human Indian hedgehog protein(IHH) (Active)

uniprot号:

规格:

5μg 25μg 100μg 250μg ￥620

图像:

基因名称:

IHH

别名:

IHH

种属:

Homo sapiens (Human)

蛋白描述:

Partial

PubMed ID:

15489334; 7590746; 7720571; 9593755; 16335952; 20519495; 21537345; 11455389; 12384778; 12632327

分子量:

19.8 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>96% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered 20 mM PB, pH 7.4, 150mM NaCl ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 3.0-10 μg/ml.

Uniprot登录名:

IHH_HUMAN

参考文献:

Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity). {ECO:0000250}.

氨基酸序列:

IIGPGRVVGS RRRPPRKLVP LAYKQFSPNV PEKTLGASGR YEGKIARSSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDRLNSLAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRNKYGLL ARLAVEAGFD WVYYESKAHV HCSVKSEHSA AAKTGG

表达区域:

29-202aa

研究领域:

Stem Cells?