产品类型:

Other

产品名称:

Recombinant Human Galectin-1 protein(LGALS1) (Active)

uniprot号:

规格:

10μg 50μg 100μg 250μg ￥620

图像:

基因名称:

LGALS1

别名:

Gal-1, HLBP14, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, Galaptin

种属:

Homo sapiens (Human)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

2719964; 2910856; 2719646; 18824694; 1988031; 12761501; 15461802; 14702039; 10591208; 15489334; 3065332; 12665801; 3611046; 1386213; 2383549; 7501023; 10369126; 10764829; 11146440; 14617626; 19497882; 19608861; 21269460; 22905912; 22223895; 22814378; 23131994; 24275569; 26091039; 15476813; 18796645; 19128029

分子量:

14.6 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>95% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered 20 mM PB, pH 7.4, 150mM NaCl ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human blood monocytes is in a concentration range of 1.0-10 ng/ml.

Uniprot登录名:

LEG1_HUMAN

参考文献:

May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. {ECO:0000269|PubMed:14617626, ECO:0000269|PubMed:18796645, ECO:0000269|PubMed:19497882}.

氨基酸序列:

ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFD

表达区域:

2-135aa

研究领域:

Cancer