产品类型:

Tumor Necrosis Factor

产品名称:

Recombinant Human Lymphotoxin-alpha protein(LTA) (Active)

uniprot号:

规格:

10μg 50μg 100μg 250μg ￥620

图像:

基因名称:

LTA

别名:

LT-alpha, Tumor necrosis factor ligand superfamily member 1

种属:

Homo sapiens (Human)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

3555974; 3001109; 3536896; 6334807; 1353024; 8499947; 10202016; 14656967; 15489334; 1451807; 1733919; 8387891; 1670638; 1671667; 12746914; 17353895

分子量:

18.7 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>96% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH7.4, with 0.02 % Tween-20 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 5 pg/ml, corresponding to a specific activity of >2.0x10⁸ IU/mg in the presence of actinomycin D.

Uniprot登录名:

TNFB_HUMAN

参考文献:

Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.

氨基酸序列:

LPGVGLTPSA AQTARQHPKM HLAHSTLKPA AHLIGDPSKQ NSLLWRANTD RAFLQDGFSL SNNSLLVPTS GIYFVYSQVV FSGKAYSPKA TSSPLYLAHE VQLFSSQYPF HVPLLSSQKM VYPGLQEPWL HSMYHGAAFQ LTQGDQLSTH TDGIPHLVLS PSTVFFGAFA L

表达区域:

35-205aa

研究领域:

Signal Transduction