产品类型:

Tumor Necrosis Factor

产品名称:

Recombinant Human Tumor necrosis factor ligand superfamily member 15 protein(TNFSF15) (Active)

uniprot号:

规格:

5μg 20μg 100μg 250μg ￥620

图像:

基因名称:

TNFSF15

别名:

TNF ligand-related molecule 1

种属:

Homo sapiens (Human)

蛋白描述:

Partial

PubMed ID:

9872942; 11923219; 11911831; 14702039; 15164053; 15489334; 9434163; 10597252; 17935696; 21300286

分子量:

20.5 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>97% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4, with 0.02% Tween-20 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by its ability to induce apoptosis using human TF-1 cells is less than 20 ng/ml, corresponding to a specific activity of >5.0x10⁴ IU/mg.

Uniprot登录名:

TNF15_HUMAN

参考文献:

Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. {ECO:0000269|PubMed:10597252, ECO:0000269|PubMed:11911831, ECO:0000269|PubMed:11923219, ECO:0000269|PubMed:9872942}.

氨基酸序列:

LKGQEFAPSH QQVYAPLRAD GDKPRAHLTV VRQTPTQHFK NQFPALHWEH ELGLAFTKNR MNYTNKFLLI PESGDYFIYS QVTFRGMTSE CSEIRQAGRP NKPDSITVVI TKVTDSYPEP TQLLMGTKSV CEVGSNWFQP IYLGAMFSLQ EGDKLMVNVS DISLVDYTKE DKTFFGAFLL

表达区域:

72-251aa

研究领域:

Cancer