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  • 产品名称:Recombinant Rhesus Macaque Tumor necrosis factor protein(TNF) (Active)

  • 产品型号:
  • 产品厂商:其它品牌
  • 产品价格:0
  • 折扣价格:0
  • 产品文档:
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简单介绍:
Recombinant Rhesus Macaque Tumor necrosis factor protein(TNF) (Active)
详情介绍:
  • 产品类型:
    Tumor Necrosis Factor
  • 产品名称:

    Recombinant Rhesus Macaque Tumor necrosis factor protein(TNF) (Active)

  • uniprot号:
  • 规格:
    ¥620
  • 图像:
  • 基因名称:
    TNF
  • 别名:
    Cachectin, Tumor necrosis factor ligand superfamily member 2, TNF-a, , NTF
  • 种属:
    Macaca mulatta (Rhesus macaque)
  • 蛋白描述:
    Partial
  • PubMed ID:
    7561102; 15269276;
  • 分子量:
    17.3 kDa
  • 标签信息:
    Tag-Free
  • 来源:
    E.Coli
  • 纯度:
    >95% as determined by SDS-PAGE and HPLC.
  • 缓冲液:
    0.2 μm filtered PBS, pH 7.4, 5 % trehalose ,lyophilized
  • 内毒素:
    Less than 1.0 EU/μg as determined by LAL method.
  • 生物活性:
    Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 0.05 ng/ml, corresponding to a specific activity of >2.0x107 IU/mg in the presence of actinomycin D.
  • Uniprot登录名:
    TNFA_MACMU
  • 参考文献:
    Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.; The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells. {ECO:0000250}.
  • 氨基酸序列:
    VRSSSRTPSD KPVAHVVANP QAEGQLQWLN RRANALLANG VELTDNQLVV PSEGLYLIYS QVLFKGQGCP SNHVLLTHTI SRIAVSYQTK VNLLSAIKSP CQRETPEGAE AKPWYEPIYL GGVFQLEKGD RLSAEINLPD YLDFAESGQV YFGIIAL
  • 表达区域:
    77-233aa
  • 研究领域:
    Cancer
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