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产品详情
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  • 产品名称:Recombinant Human Oncostatin-M protein(OSM) (Active)

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简单介绍:
Recombinant Human Oncostatin-M protein(OSM) (Active)
详情介绍:
  • 产品类型:
    Growth Factor
  • 产品名称:

    Recombinant Human Oncostatin-M protein(OSM) (Active)

  • uniprot号:
  • 规格:
    ¥620
  • 图像:
  • 基因名称:
    OSM
  • 别名:
    OSM
  • 种属:
    Homo sapiens (Human)
  • 蛋白描述:
    Partial
  • PubMed ID:
    2779549; 15461802; 10591208; 15489334; 3540948; 1542792; 2325640; 2026606; 1717982; 1542793; 8999038; 10997905
  • 分子量:
    23.7 kDa
  • 标签信息:
    Tag-Free
  • 来源:
    E.Coli
  • 纯度:
    >97% as determined by SDS-PAGE and HPLC.
  • 缓冲液:
    0.2 μm filtered PBS, pH 7.4 ,lyophilized
  • 内毒素:
    Less than 1.0 EU/μg as determined by LAL method.
  • 生物活性:
    Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 2 ng/ml, corresponding to a specific activity of >5.0x105 IU/mg.
  • Uniprot登录名:
    ONCM_HUMAN
  • 参考文献:
    Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). {ECO:0000250}.
  • 氨基酸序列:
    AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRRHSPH QALRKGVRR
  • 表达区域:
    26-234aa
  • 研究领域:
    Immunology
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