产品详情
简单介绍:
Recombinant Human CD40 ligand protein(CD40LG) (Active)
详情介绍:
Tumor Necrosis Factor
Recombinant Human CD40 ligand protein(CD40LG) (Active)
¥620
CD40LG
CD40-L, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, CD antigen CD154
Homo sapiens (Human)
Partial
1280226; 1385114; 7678782; 1281209; 7678552; 7999797; 15489334; 8626375; 11676606; 15193700; 8589998; 9605317; 7679206; 8094231; 7679801; 7717401; 7532185; 8889581; 8550833; 9150729; 9746782
16.3 kDa
Tag-Free
E.Coli
>95% as determined by SDS-PAGE and HPLC.
0.2 μm filtered PBS, pH 7.0 ,lyophilized
Less than 1.0 EU/μg as determined by LAL method.
Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 5-10 ng/ml.
CD40L_HUMAN
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. {ECO:0000269|PubMed:15193700}.; Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway. {ECO:0000269|PubMed:15193700}.
MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LWLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL
113-261aa
Cancer
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