产品类型:

Tumor Necrosis Factor

产品名称:

Recombinant Human Tumor necrosis factor receptor superfamily member 13B protein(TNFRSF13B) (Active)

uniprot号:

规格:

5μg 20μg 100μg 250μg ￥620

图像:

基因名称:

TNFRSF13B

别名:

Transmembrane activator and CAML interactor

种属:

Homo sapiens (Human)

蛋白描述:

Partial

PubMed ID:

9311921; 14702039; 15489334; 10956646; 10973284; 10880535; 15542592; 16007086; 21248752

分子量:

18.0 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>95% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The biological activity is determined by its ability to block human BAFF induced T2B cell survival using a concentration range of 1.0-3.0 ug/ml.

Uniprot登录名:

TR13B_HUMAN

参考文献:

Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. {ECO:0000269|PubMed:10956646, ECO:0000269|PubMed:10973284}.

氨基酸序列:

MSGLGRSRRG GRSRVDQEER FPQGLWTGVA MRSCPEEQYW DPLLGTCMSC KTICNHQSQR TCAAFCRSLS CRKEQGKFYD HLLRDCISCA SICGQHPKQC AYFCENKLRS PVNLPPELRR QRSGEVENNS DNSGRYQGLE HRGSEASPAL PGLKLSADQV

表达区域:

1-160aa

研究领域:

Cancer