产品类型:

Chemokine

产品名称:

Recombinant Human C-C motif chemokine 25 protein(CCL25) (Active)

uniprot号:

规格:

5μg 20μg 100μg 250μg ￥620

图像:

基因名称:

CCL25

别名:

Chemokine TECK, Thymus-expressed chemokine

种属:

Homo sapiens (Human)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

9285413; 14702039; 15057824; 15489334; 10229797; 23341447

分子量:

14.3 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>97% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10 ng/ml.

Uniprot登录名:

CCL25_HUMAN

参考文献:

Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

氨基酸序列:

M+QGVFEDCCL AYHYPIGWAV LRRAWTYRIQ EVSGSCNLPA AIFYLPKRHR KVCGNPKSRE VQRAMKLLDA RNKVFAKLHH NTQTFQAGPH AVKKLSSGNS KLSSSKFSNP ISSSKRNVSL LISANSGL

表达区域:

24-150aa

研究领域:

Immunology