产品详情
简单介绍:
Recombinant Mouse C-C motif chemokine 25 protein(Ccl25) (Active)
详情介绍:
Chemokine
Recombinant Mouse C-C motif chemokine 25 protein(Ccl25) (Active)
¥620
Ccl25
Chemokine TECK, Thymus-expressed chemokine
Mus musculus (Mouse)
Full Length of Mature Protein
9285413; 10602049; 16517733; 16141072; 19468303; 15489334
14.1 kDa
Tag-Free
E.Coli
>95% as determined by SDS-PAGE and HPLC.
0.2 μm filtered PBS, pH 7.4 ,lyophilized
Less than 1.0 EU/μg as determined by LAL method.
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 5.0-50 ng/ml.
CCL25_MOUSE
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
QGAFEDCCLG YQHRIKWNVL RHARNYHQQE VSGSCNLRAV RFYFRQKVVC GNPEDMNVKR AIRILTARKR LVHWKSASDS QTERKKSNHM KSKVENPNST SVRSATLGHP RMVMMPRKTN N
24-144aa
Immunology
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