产品类型:

Interleukin

产品名称:

Recombinant Rhesus Macaque Interleukin-6 protein(IL6) (Active)

uniprot号:

规格:

2μg 10μg 100μg 250μg ￥620

图像:

基因名称:

IL6

别名:

IL-6

种属:

Macaca mulatta (Rhesus macaque)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

7561102

分子量:

21.1 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>97% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay usingIL-6-dependent murine 7TD1 cells is less than 0.1 ng/ml, corresponding to a specific activity of >1.0x10⁷ IU/mg.

Uniprot登录名:

IL6_MACMU

参考文献:

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation (By similarity). {ECO:0000250}.

氨基酸序列:

M+APVLPGEDS KNVAAPHSQP LTSSERIDKH IRYILDGISA LRKETCNRSN MCESSKEALA ENNLNLPKMA EKDGCFQSGF NEDTCLVKII TGLLEFEVYL EYLQNRFESS EEQARAVQMS TKVLIQFLQK KAKNLDAITT PEPTTNASLL TKLQAQNQWL QDMTTHLILR SFKEFLQSNL RALRQM

表达区域:

28-212aa

研究领域:

Immunology