产品详情
简单介绍:
Recombinant Rhesus Macaque Pro-interleukin-16 [Cleaved into: Interleukin-16 protein(IL16) (Active)
详情介绍:
Interleukin
Recombinant Rhesus Macaque Pro-interleukin-16 [Cleaved into: Interleukin-16 protein(IL16) (Active)
¥620
![](http://zt.yzimgs.com/313862/images/201805/201805221851509194.jpg)
IL16
IL-16, LCF,]
Macaca mulatta (Rhesus macaque)
Full Length of Mature Protein
9510557
12.5 kDa
Tag-Free
E.Coli
>98% as determined by SDS-PAGE and HPLC.
0.2 μm filtered PBS, pH 7.4 ,lyophilized
Less than 1.0 EU/μg as determined by LAL method.
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral T lymphocytes is in a concentration range of 1.0-100 ng/ml.
IL16_MACMU
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). {ECO:0000250}.; Pro-interleukin-16 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells (By similarity). {ECO:0000250}.
SAASASAASD VSVESSAEAT VYTVTLEKMS AGLGFSLEGG KGSLHGDKPL TINRIFKGAA SEQSETIQPG DEILQLAGTA MQGLTRFEAW NIIKALPDGP VTIVIRRKSL QPKETTAAAD S
510-630aa
Immunology
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