产品类型:

Interleukin

产品名称:

Recombinant Rhesus Macaque Pro-interleukin-16 [Cleaved into: Interleukin-16 protein(IL16) (Active)

uniprot号:

规格:

2μg 10μg 100μg 250μg ￥620

图像:

基因名称:

IL16

别名:

IL-16, LCF,]

种属:

Macaca mulatta (Rhesus macaque)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

9510557

分子量:

12.5 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>98% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral T lymphocytes is in a concentration range of 1.0-100 ng/ml.

Uniprot登录名:

IL16_MACMU

参考文献:

Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). {ECO:0000250}.; Pro-interleukin-16 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells (By similarity). {ECO:0000250}.

氨基酸序列:

SAASASAASD VSVESSAEAT VYTVTLEKMS AGLGFSLEGG KGSLHGDKPL TINRIFKGAA SEQSETIQPG DEILQLAGTA MQGLTRFEAW NIIKALPDGP VTIVIRRKSL QPKETTAAAD S

表达区域:

510-630aa

研究领域:

Immunology