产品类型:

Interleukin

产品名称:

Recombinant Human Interleukin-31 protein(IL31) (Active)

uniprot号:

规格:

2μg 10μg 100μg 250μg ￥620

图像:

基因名称:

IL31

别名:

IL-31

种属:

Homo sapiens (Human)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

15184896; 15489334; 16461143; 17030248

分子量:

15.8 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>97% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The specific activity is determined by inducing STAT3 activation using human U-87 MG cells. 5 ng/mL of rHuIL-31 can effectively induce STAT3 activation.

Uniprot登录名:

IL31_HUMAN

参考文献:

Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. {ECO:0000269|PubMed:15184896}.

氨基酸序列:

SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T

表达区域:

24-164aa

研究领域:

Immunology