产品类型:

Colony Stimulating Factor

产品名称:

Recombinant Human EPO-alpha/Fc Chimera protein(EPOFc) (Active)

uniprot号:

规格:

2μg 10μg 100μg 250μg ￥620

基因名称:

EPO

别名:

Epoetin

种属:

Homo sapiens (Human)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

3838366; 3865178; 9799793; 12853948; 15489334; 8396923; 3949763; 6698989; 3346214; 3219367; 1820196; 11739166; 9774108; 9783743; 18458324

分子量:

45.3 kDa

标签信息:

C-terminal FC-tagged

来源:

Mammalian cell

纯度:

>98% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2μm filtered sodium citrate buffer (1 liter of ddH2O containing 5.9 g of sodium citrate, 5.8 g of sodium chloride and 0.06 g of citric acid) ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using human megakaryoblastic leukemia cells is less than 2 ng/ml, corresponding to a specific activity of >5.0x10⁵ IU/mg.

Uniprot登录名:

EPOFc_HUMAN

参考文献:

Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.

氨基酸序列:

APPRLICDSRVLERYLLEAKEAENITTGCAEHCSLNENITVPDTKVNFYAWKRMEVGQQAVEVWQGLALL
SEAVLRGQALLVNSSQPWEPLQLHVDKAVSGLRSLTTLLRALGAQKEAISPPDAASAAPLRTITADTFRK
LFRVYSNFLRGKLKLYTGEACRTGDR+IEGRMDEPKSSDKTHTCPPCPAPEFEGAPSVFLFPPKPKDTLM
ISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCK
VSNKALPTPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYK
TTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

表达区域:

28-193aa

研究领域:

Cancer