产品类型:

Chemokine

产品名称:

Recombinant Human C-C motif chemokine 8 protein(CCL8) (Active)

uniprot号:

规格:

2μg 10μg 100μg 250μg ￥620

图像:

基因名称:

CCL8

别名:

HC14, Monocyte chemotactic protein 2, MCP-2, Small-inducible cytokine A8

种属:

Homo sapiens (Human)

蛋白描述:

Full Length of Mature Protein

PubMed ID:

9119400; 9070881; 15489334; 2518726; 1613466; 8898111; 9558113; 11087354

分子量:

8.9 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>96% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 10-100 ng/ml.

Uniprot登录名:

CCL8_HUMAN

参考文献:

Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. {ECO:0000269|PubMed:9558113}.

氨基酸序列:

QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP

表达区域:

24-99aa

研究领域:

Immunology