产品类型:

Chemokine

产品名称:

Recombinant Human C-C motif chemokine 13 protein(CCL13) (Active)

uniprot号:

规格:

5μg 20μg 100μg 250μg ￥620

图像:

基因名称:

CCL13

别名:

CK-beta-10, Monocyte chemotactic protein 4, MCP-4, NCC-1, Small-inducible cytokine A13

种属:

Homo sapiens (Human)

蛋白描述:

Partial

PubMed ID:

8955214; 8642349; 9195948; 9060459; 10049733; 16625196; 15489334; 18323622

分子量:

8.6 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>96% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 10-100 ng/ml.

Uniprot登录名:

CCL13_HUMAN

参考文献:

Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.

氨基酸序列:

QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT

表达区域:

24-98aa

研究领域:

Immunology