产品类型:

Chemokine

产品名称:

Recombinant Human C-C motif chemokine 14 protein(CCL14) (Active)

uniprot号:

规格:

2μg 10μg 100μg 250μg ￥620

图像:

基因名称:

CCL14

别名:

Chemokine CC-1/CC-3, HCC-11-74 NCC-2, Small-inducible cytokine A14

种属:

Homo sapiens (Human)

蛋白描述:

Partial

PubMed ID:

8551235; 9600961; 10213461; 15489334; 10978165; 11085751; 17691823

分子量:

8.4 kDa

标签信息:

Tag-Free

来源:

E.Coli

纯度:

>96% as determined by SDS-PAGE and HPLC.

缓冲液:

0.2 μm filtered PBS, pH 7.4 ,lyophilized

内毒素:

Less than 1.0 EU/μg as determined by LAL method.

生物活性:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-20 ng/ml.

Uniprot登录名:

CCL14_HUMAN

参考文献:

Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. {ECO:0000269|PubMed:11085751}.

氨基酸序列:

TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN

表达区域:

22-93aa

研究领域:

Immunology